This page lists our custom-loaded Kids First projects by cancer_study_identifier and name and lists out release notes each time the project is updated. Common updates include new/improved clinical data, genomic data, as well as any bug fixes.
Table of Contents
ijaz_cole_2019: Pediatric high-grade glioma resources from the Children's Brain Tumor Tissue Consortium (CHOP, Publication)
- July 1, 2021: 🎉 Initial release
- July 22, 2021:
- 🐛 Bug fix - RNAseq z scores were done across genes by sample, instead of vice-versa. The update fixes that
- 📝 Change
GENDER to SEX as flexibility between the two terms is now deprecated
pbta_all: Pediatric Brain Tumor Atlas (PBTA, Provisional)
- February 1, 2020: 🎉 Initial release
- April 23, 2021: 🐛 Fixed CNV values for samples with ploidy > 2, which cause an inflated number of losses to be reported
- June 9, 2021: 🐛 This update fixes RNAseq Z score to be by gene and not sample
- WARNING! This fix was unsuccessful and did the exact opposite. Load from July 23, 2021 actually fixes this bug
- July 1, 2021: ✨ Begun expansion of data availability with a pilot addition of consented clinical research panel data
- July 23, 2021: 🔧 Fixed z score bug, added a couple additional clinical sequencing samples
- September 8, 2021: 🎆 Addition of all available consented clinical sequencing research subject
- September 13, 2021: 🔨
- Removed non-brain tumor samples from study
- Added in matched normal sample IDs
- Improved CANCER_TYPE display, removing repeat diagnoses
- September 23, 2021: 🚀
- Added DGD Fusion files
- Added additional DGD MAF files
- October 13, 2021: 📝
- Updated missing diagnosis data for a subset of samples
- February 14, 2022: 💪
- Added new samples processed since last load
- General updates to metadata to existing samples
- April 28, 2022: 🐛
- Applied fusion load fix for cBio display bug
- Loaded latest patient metadata updates for CBTN subjects
- Added latest additions to PBTA
- October 16, 2022: 💪
- Dropped clinical sequencing samples due to gene naming conflicts (will add back once resolved)
- Added molecular subtypes and histologies from OpenPedCan
- Re-mapped
TUMOR_TYPE to fit cBio functionality, maintained original values in new column, CBTN_TUMOR_TYPE
- General clinical data updates